Product Introduction:
Valsartan is used clinical for receptor antagonist of angiotensin AT1, has good effect to the different degree of hypertension patients who used other antihypertensive drugs without efficacy , is a new generation of highly efficient antihypertensive drugs.
| Product Name | High quality Valsartan 137862-53-4 with reasonable price on sale |
| Appearance |
Crystalline powder |
| Assay | 99% |
| Certificate | ISO 9001 |
| Test | HPLC |
| Packing | Bag, drum |
| MF | C24H29N5O3 |
| StorageTemperature | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
| Product Name | Valsartan | |||
| Reference | USP | |||
| Test Items | Specifications | Results | ||
| Characters | Description | White or off-white powder. Odorless. | White powder. Odorless | |
| *Slightly hygroscopy. | Conform | |||
| *Solubility | Freely soluble in ethanol, sparingly soluble in et hyl acetate, slightly soluble in dichlo romethane, practically insoluble in water | Conform | ||
| Identification | 1) Infrared absorption spectrophotometry: corresponds to the reference standard. | Conform | ||
| 2) The retention time of the major peak in the chromatogram of the assay preparation corresponds to that of the standard preparation, as obtained in the Assay. | Conform | |||
| Water (KF) | ≤2.0% | 0.3% | ||
| Absorbance | ≤0.02 (λ=420nm, C=0.05g/ml, L=1cm) | <0.01 | ||
| Residue on ignition | ≤0.1% | <0.1% | ||
| D-Valsartan (HPLC) | ≤1.0% | 0.22% | ||
| Related substances (HPLC) | Butyryl-Valsartan ≤0.2% | 0.01% | ||
| Benzyl-Valsartan ≤0.1% | <LOD(LOD:0.02%) | |||
| Any other individual impurity≤0.10% | 0.03% | |||
| Total impurities excluding D-Valsartan≤0.3% | 0.06% | |||
| Residual solvents (GC) | Ethanol≤5000ppm | <LOD(LOD:2ppm) | ||
| Ethyl ace tate≤5000ppm | 3149ppm | |||
| Tolue ne≤890ppm | 19ppm | |||
| Assay (HPLC) | 98.0-102.0% (calculated on anhydrous,solvent-free basis) | 100.7% | ||
| Conclusion | Complies with USP | |||