Descriptions
Tetracycline hydrochloride is the hydrochloride form of the tetracycline. Tetracycline is a kind of broad-spectrum polyketide antibiotics produced by the Streptomyces genus of antinobacteria. It is a kind of bacteriostatic antibiotics which inhibits the bacteria growth through binding to the 30 S ribosomal subunit, blocking the aminoacyl tRNA from binding to the translating ribosome, thus interfering with the protein synthesis process. It is used for the treatment of infections occurring in urinary tracts, respiratory tract, and the intestines. Because of the problem of drug resistance, tetracycline is not a frequent choice for treating bacterial infections. However, it is still used for the treatment of infections caused by chlamydia, Rickettsia and Spirochetal.
Product Info:
| Product Name | Tetracycline Hcl |
| CAS No | 64-75-5 |
| MF | C22H23ClN2O8.HCl |
| Color | Yellow Powder |
| Purity | 99% |
Application
1.Previously Tetracycline Hcl were used for a variety of common infections, including bacterial gastroenteritis, pneumonia and urinarytract infections. However, numerous strains of bacteria causing these infections now are resistant and other agents have mostly superseded tetracyclines.
2.This product is broad-spectrum antimicrobial agents, high concentrations of sterilization.
COA
|
Item |
Standard |
Result |
|
Characteristics |
A white or yellowish white powder .Odorless or almost.bygroscopic |
Conforms |
|
Identification |
A:B:C The positive reaction. |
Conforms |
|
Solubility |
Very soluble in water, insoluble in acetone , ether. |
Conforms |
|
Specific optical rotation |
+53.5°~ +59.0° |
+58.0° |
|
Acidity of alkalinity |
5.0~7.5 |
6.7 |
|
Impurity A |
2%max |
Conforms |
|
Impurity C |
3% ~15% |
Conforms |
|
Any other impurity |
not more than the area of the principal peak |
Conforms |
|
in the chromatogram obtained with RS(B)5% |
||
|
Total other impurity |
not more than 3times the area of the principal peak |
Conforms |
|
in the chromatogram obtained with RS(B)15% |
||
|
Disregard limit |
ae of the principal peak in the chromatogram |
Conforms |
|
obtained with RS(C)1% |
||
|
Loss on drying (pct) |
max8.0 |
5.0% |
|
Sulphate |
27.0-31.0% |
28.4%max |
|
Sulphated ash |
1% max |
0.2% |
|
Microcount limit test |
NMT 500 col/g |
10 col/g |
|
Microcount-yeast and molds |
NMT 10 col/g |
Conforms |
|
Microcount-Escherichia coli |
Absent |
Conforms |
|
Microcount-Staphy lococcus aureus |
Absent |
Conforms |
|
Microcount-Pseudo monas |
Absent |
|
|
Assay |
≥680I.U./mg (DRY) |
687I.U./mg DRY 653I.U./mg MOIST |
200kg Powder Packaging
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