CAS 83881 -52-1 Cetirizine Hydrochloride Cetirizine HCl

Model NO.
cetirizine
Name
Cetirizine HCl
Transport Package
Drum
Specification
99%
Trademark
HS
Origin
China
HS Code
2904201000
Production Capacity
100000
Reference Price
$ 97.20 - 108.00
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Product Description

CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl

1. Product Name: Cetirizine Hydrochloride
2.Purity: 99%
3.Molecular Weight: 461.81
4.Test method: HPLC
5.Appearance: White Powder
6.Melting point: 110-115°C
7.Water Solubility: Soluble in water, DMSO, ethanol, and methanol.
8.Introduction:
Cetirizine hydrochloride is an orally-active and selective histamine (H1)-receptor antagonist. It is a second-generation antihistamine and a human metabolite of hydroxyzine. Three important features of cetirizine are: a high specificity fort he H1-receptor; a low need for metabolism, and the existence of non-H1-dependent activities on cells involved in the pathogenesis of allergy.
 
CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl

Cetirizine is a second generation antihistamine used in the treatment of hay fever, allergies, angioedema, and urticaria.It is a major metabolite of hydroxyzine, and a racemicselective H1 receptor antagonist.

1. Cetirizine is mainly used for urticaria and skin itch caused by allergy ;
2. Cetirizine is used to treat tardive and pressure urticaria,can replace glucocorticoid to be as regular treatment but should be used a large amount;
3. Cetirizine can also have the function for cold urticaria.  
CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl
TEST
SPECIFICATION
RESULT
Appreance
White or almost white powder
almost white powder
Identification
Postitive
confirms
pH
1.2-1.8
1.54
Loss on drying
≤0.5%
0.15%
Residue on Ignition
≤0.2%
0.03%
Clolor of Solution
≤BY7
confirms
Heavy metals
≤10ppm
confirms
Single Impurity
≤0.1%
0.10%
Total Impurity
≤0.3%
0.28%
Assay
99%-100.5%
99.78%
Aceton
≤0.5%
0.01%
CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl

 

Pharmaceutical Intermediate

LEGALIS.IT, 2023